Jumbo Heart

Info
Jumbo Heart has a whopping 40 HP, twice that of a Lesser Heart. This allows it to tank much more punishment before dying. Jumbo Heart can be obtained from shops and item rooms.

Strategies
Jumbo Heart is a top tier heart because of its survivability. You always want this as the right-most heart (there can be a few more considerations when Jello Heart or Tough Heart are involved). Preserving this heart is extremely essential to a good run. Always swap it out whenever it is heavily damaged and if possible don't even swap it into the second slot. If used correctly, this heart should survive for a large portion of Dream.

Trivia

 * This heart has the most health out of all regenerating hearts
 * In earlier versions this heart's sprite was just a bigger Lesser Heart (as opposed to having a color and size change)